Improvement of function and morphology of tumor necrosis factor-α treated endothelial cells with 17-β estradiol - A preliminary study for a feasible simple model for atherosclerosis

• Main Authors: Parin Suwannaprapha, Urai Chaisri, Doungrat Riyong, Yaowapa Maneerat
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=20444421551&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62103
• Institution: Chiang Mai University

Background: Dysfunction of endothelial cells (EC) to produce endothelial nitric oxide synthase (eNOS) by tumor necrosis factor-α (TNF-α) causes critical features of vascular inflammation associated with several disease states (eg, atherosclerosis including increased platelet aggregation and adhesion...