Exploiting sequential injection analysis with lab-at-valve (LAV) approach for on-line liquid-liquid micro-extraction spectrophotometry

• Main Authors: Rodjana Burakham, Somchai Lapanantnoppakhun, Jaroon Jakmunee, Kate Grudpan
• Format: Journal
• Published: 2018
• Subjects: Chemistry
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=27744511664&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62137
• Institution: Chiang Mai University

Sequential injection analysis (SIA) with lab-at-valve (LAV) approach for on-line liquid-liquid micro-extraction has been exploited. Sample, reagent and organic solvent were sequentially aspirated into a coil attached to a central port of a conventional multiposition selection valve, where the extraction process was performed. The aqueous and organic phases were separated in a conical separating chamber LAV unit attached at one port of the valve. The organic phase containing extracted product was then monitored spectrophotometrically. The system offers a novel alternative on-line automated extraction in a micro-scale and has been successfully demonstrated for the assays of diphenhydramine hydrochloride (DPHH) in pharmaceutical preparations and anionic surfactant in water samples. © 2005 Published by Elsevier B.V.