Inhibition of P-glycoprotein function and expression by kaempferol and quercetin

The 170 kDa plasma membrane P-glycoprotein (Pgp) causes the efflux of chemotherapeutic drugs from cells and is believed to be an important mechanism in multidrug resistance (MDR) in human cancer. This study demonstrates that some putative flavonoids, i.e., flavonols (quercetin and kaempferol) and is...

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Bibliographic Details
Main Authors: P. Limtrakul, O. Khantamat, K. Pintha
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=16244371036&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/62433
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Institution: Chiang Mai University