Deciphering critical amino acid residues to modify and enhance the binding affinity of ankyrin scaffold specific to capsid protein of human immunodeficiency virus type 1

• Main Authors: Somphot Saoin, Tanchanok Wisitponchai, Kannaporn Intachai, Koollawat Chupradit, Sutpirat Moonmuang, Sawitree Nangola, Kuntida Kitidee, Kanda Fanhchaksai, Vannajan Sanghiran Lee, Saw See Hong, Pierre Boulanger, Phimonphan Chuankhayan, Chun Jung Chen, Chatchai Tayapiwatana
• 格式: 雜誌
• 出版: 2018
• 主題: Immunology and Microbiology; Medicine
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85053791498&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62744
• 機構: Chiang Mai University

© 2018, Allergy and Immunology Society of Thailand. All rights reserved. Background: AnkGAG1D4 is an artificial ankyrin repeat protein which recognizes the capsid protein (CA) of the human immunodeficiency virus type 1 (HIV-1) and exhibits the intracellular antiviral activity on the viral assembly p...