Anti-proliferative effect of 8α-tigloyloxyhirsutinolide-13-O-acetate (8αTGH) isolated from Vernonia cinerea on oral squamous cell carcinoma through inhibition of STAT3 and STAT2 phosphorylation

• Main Authors: Phisit Pouyfung, Sirinthip Choonate, Ariyaphong Wongnoppavich, Pornpimol Rongnoparut, Kongthawat Chairatvit
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055619701&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62909
• Institution: Chiang Mai University

© 2018 Elsevier GmbH Background: The high mortality rate of oral cancers has stimulated the search for effective herbal medicines and their pharmacological targets. Vernonia cinerea, a perennial tropical herb, is wildly used as a traditional folk medicine for treatment of intestinal diseases and var...