5-Oxo-hexahydroquinoline derivatives as modulators of P-gp, MRP1 and BCRP transporters to overcome multidrug resistance in cancer cells

• Main Authors: Sara Ranjbar, Ruttiros Khonkarn, Alexis Moreno, Hélène Baubichon-Cortay, Ramin Miri, Mehdi Khoshneviszadeh, Luciano Saso, Najmeh Edraki, Pierre Falson, Omidreza Firuzi
• Format: Journal
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85056449999&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62943
• Institution: Chiang Mai University

© 2018 Elsevier Inc. Multidrug resistance (MDR) in cancer cells is often associated with overexpression of ATP-binding cassette (ABC) transporters, including P-glycoprotein (P-gp/ABCB1), multidrug resistance-associated protein 1 (MRP1/ABCC1) and breast cancer resistance protein (BCRP/ABCG2). Modulat...