Glycan binding and specificity of viral influenza neuraminidases by classical molecular dynamics and replica exchange molecular dynamics simulations

• Main Authors: Jiraphorn Phanich, Siraphob Threeracheep, Nawee Kungwan, Thanyada Rungrotmongkol, Supot Hannongbua
• Format: Journal
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057574035&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/62960
• Institution: Chiang Mai University

© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Two important glycoproteins on the influenza virus membrane, hemagglutinin (HA) and neuraminidase (NA), are relevant to virus replication. As previously reported, HA has a substrate specificity towards SIA-2,3-GAL-1,4-NAG (3...