Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective

© 2017 by Taylor & Francis Group, LLC. The implantation of a bioresorbable scaffolds (BRSs) is a new approach that provides transient vessel support with drug delivery capability, potentially without the limitations of permanent metallic implants [1]. The potential short- and long-term perform...

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Main Authors: Yohei Sotomi, Pannipa Suwannasom, Jouke Dijkstra, Carlos Collet, Shimpei Nakatani, Patrick W.J.C. Serruys, Yoshinobu Onuma
Format: Book
Published: 2018
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/62992
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-629922018-12-14T04:20:40Z Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective Yohei Sotomi Pannipa Suwannasom Jouke Dijkstra Carlos Collet Shimpei Nakatani Patrick W.J.C. Serruys Yoshinobu Onuma Biochemistry, Genetics and Molecular Biology © 2017 by Taylor & Francis Group, LLC. The implantation of a bioresorbable scaffolds (BRSs) is a new approach that provides transient vessel support with drug delivery capability, potentially without the limitations of permanent metallic implants [1]. The potential short- and long-term performance of this technology has been repeatedly investigated with optical coherence tomography (OCT) [2-7]. However, images acquired by OCT after implantation of BRSs are different from those with metallic stents due to the translucency of polymeric materials compared to the opacity of metallic compounds (Figure 5.3.1). Metallic struts appear on OCT as a reflective leading structure with abluminal shadowing, while polymeric struts appear as a “black box” area surrounded by bright reflecting frames without abluminal shadowing. As a consequence, in polymeric scaffolds the vessel wall behind the struts and the luminal area can easily be imaged and assessed, contributing to several advantages in quantitative analysis: (1) capability of measuring the lumen vessel wall interface at baseline; (2) accurate assessment of malapposed struts; (3) measurement of strut/strut core area; (4) precise measurements of flow area; and (5) measurement of neointimal area between and on top of the struts. 2018-12-14T04:20:40Z 2018-12-14T04:20:40Z 2017-01-01 Book 2-s2.0-85055381156 10.1201/9781315380629 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055381156&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/62992
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
spellingShingle Biochemistry, Genetics and Molecular Biology
Yohei Sotomi
Pannipa Suwannasom
Jouke Dijkstra
Carlos Collet
Shimpei Nakatani
Patrick W.J.C. Serruys
Yoshinobu Onuma
Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective
description © 2017 by Taylor & Francis Group, LLC. The implantation of a bioresorbable scaffolds (BRSs) is a new approach that provides transient vessel support with drug delivery capability, potentially without the limitations of permanent metallic implants [1]. The potential short- and long-term performance of this technology has been repeatedly investigated with optical coherence tomography (OCT) [2-7]. However, images acquired by OCT after implantation of BRSs are different from those with metallic stents due to the translucency of polymeric materials compared to the opacity of metallic compounds (Figure 5.3.1). Metallic struts appear on OCT as a reflective leading structure with abluminal shadowing, while polymeric struts appear as a “black box” area surrounded by bright reflecting frames without abluminal shadowing. As a consequence, in polymeric scaffolds the vessel wall behind the struts and the luminal area can easily be imaged and assessed, contributing to several advantages in quantitative analysis: (1) capability of measuring the lumen vessel wall interface at baseline; (2) accurate assessment of malapposed struts; (3) measurement of strut/strut core area; (4) precise measurements of flow area; and (5) measurement of neointimal area between and on top of the struts.
format Book
author Yohei Sotomi
Pannipa Suwannasom
Jouke Dijkstra
Carlos Collet
Shimpei Nakatani
Patrick W.J.C. Serruys
Yoshinobu Onuma
author_facet Yohei Sotomi
Pannipa Suwannasom
Jouke Dijkstra
Carlos Collet
Shimpei Nakatani
Patrick W.J.C. Serruys
Yoshinobu Onuma
author_sort Yohei Sotomi
title Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective
title_short Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective
title_full Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective
title_fullStr Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective
title_full_unstemmed Optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: A core lab perspective
title_sort optical coherence tomography analysis of bioresorbable vascular scaffolds in comparison with metallic stents: a core lab perspective
publishDate 2018
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055381156&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/62992
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