Hepatoprotective effect of coffee pulp aqueous extract combined with simvastatin against hepatic steatosis in high-fat diet-induced obese rats

• Main Authors: Atcharaporn Ontawong, Oranit Boonphang, Tipthida Pasachan, Acharaporn Duangjai, Anchalee Pongchaidecha, Manussaborn Phatsara, Metee Jinakote, Doungporn Amornlerdpison, Chutima Srimaroeng
• Format: Journal
• Published: 2019
• Subjects: Agricultural and Biological Sciences; Medicine; Nursing
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85061253732&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/63531
• Institution: Chiang Mai University

© 2019 Elsevier Ltd This study investigated the effect of coffee pulp aqueous extract (CPE) on obesity- induced hepatic steatosis in rats and the mechanism involved. Male Wistar rats were fed high-fat diet for 12 weeks and supplemented with 1000 mg/kg BW CPE or 40 mg/kg BW simvastatin or CPE combine...