Activation of sirtuin 3 and maintenance of mitochondrial integrity by N-acetylcysteine protects against bisphenol A-induced kidney and liver toxicity in rats

• Main Authors: Wachirasek Peerapanyasut, Anongporn Kobroob, Siripong Palee, Nipon Chattipakorn, Orawan Wongmekiat
• Format: Journal
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Computer Science
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85060055383&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/63581
• Institution: Chiang Mai University

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Mitochondrial impairment ensuing from oxidative imbalance is related to adverse consequences of bisphenol A (BPA), a globally utilized industrial chemical. Recent evidence reveals sirtuin 3 (SIRT3) as a key regulator of mitochondrial homeosta...