Designed antiviral ankyrin – A computational approach to combat HIV-1 via intracellular pathway by targeting the viral capsid of HIV-1

• Main Authors: Hana Atiqah Abdul Karim, Thanyada Rungrotmongkol, Sharifuddin M. Zain, Noorsaadah Abd Rahman, Chatchai Tayapiwattana, Vannajan Sanghiran Lee
• Format: Journal
• Published: 2019
• Subjects: Chemistry; Materials Science; Physics and Astronomy
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059192572&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/63612
• Institution: Chiang Mai University

© 2018 Elsevier B.V. Scaffold known as designed ankyrin repeat proteins (DARPins) have been utilized by scientists extensively in protein binding, as they acquire remarkable binding properties. Trimodular ankyrin repeat protein (Ank1D4) is a potential macromolecular and antiviral intracellular inhi...