Molecular Docking Study of Phthalimide Derivatives as Non-nucleoside HIV-1 Reverse Transcriptase Inhibitor

• المؤلفون الرئيسيون: Pimonluck Sittikornpaiboon, Pisanu Toochinda, Chawanee Thongpanchang, Ubolsree Leartsakulpanich, Luckhana Lawtrakul
• التنسيق: บทความวารสาร
• اللغة: English
• منشور في: Science Faculty of Chiang Mai University 2019
• الوصول للمادة أونلاين: http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=7351; http://cmuir.cmu.ac.th/jspui/handle/6653943832/63791
• المؤسسة: Chiang Mai University

The molecular docking approach was used to determine the binding affinities and the interactions of Mycobacterium tuberculosis dihydrofolate reductase (mtbDHFR) in complex with 2, 4-diaminopyrimidines analogues (PYR analogous). This approach can classify compounds into low and high affinity agents w...