Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium
An efficient and simple cyclocondensation approach for the one-pot, three-component synthesis of 3,4-disubtituted isoxazole-5(4H)-ones has been described. This three-component reaction was completed easily and cleanly to give corresponding isoxazoles in the presence of Ni(OAc)2.H2O as the catalyst....
Saved in:
| Main Authors: | , |
|---|---|
| Format: | บทความวารสาร |
| Language: | English |
| Published: |
Science Faculty of Chiang Mai University
2019
|
| Online Access: | http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8289 http://cmuir.cmu.ac.th/jspui/handle/6653943832/63929 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Chiang Mai University |
| Language: | English |
| id |
th-cmuir.6653943832-63929 |
|---|---|
| record_format |
dspace |
| spelling |
th-cmuir.6653943832-639292019-05-07T09:59:39Z Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium Hamzeh Kiyani Heshmat Allah Samimi An efficient and simple cyclocondensation approach for the one-pot, three-component synthesis of 3,4-disubtituted isoxazole-5(4H)-ones has been described. This three-component reaction was completed easily and cleanly to give corresponding isoxazoles in the presence of Ni(OAc)2.H2O as the catalyst. The reaction was implemented in aqueous media at room temoerature and the corresponding heterocyclic were obtained in good to high yields. The present work offers notable advantages, including easy work-up, simple procedure, mild condition, and no use of organic solvents. 2019-05-07T09:59:39Z 2019-05-07T09:59:39Z 2017 บทความวารสาร 0125-2526 http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8289 http://cmuir.cmu.ac.th/jspui/handle/6653943832/63929 Eng Science Faculty of Chiang Mai University |
| institution |
Chiang Mai University |
| building |
Chiang Mai University Library |
| country |
Thailand |
| collection |
CMU Intellectual Repository |
| language |
English |
| description |
An efficient and simple cyclocondensation approach for the one-pot, three-component synthesis of 3,4-disubtituted isoxazole-5(4H)-ones has been described. This three-component reaction was completed easily and cleanly to give corresponding isoxazoles in the presence of Ni(OAc)2.H2O as the catalyst. The reaction was implemented in aqueous media at room temoerature and the corresponding heterocyclic were obtained in good to high yields. The present work offers notable advantages, including easy work-up, simple procedure, mild condition, and no use of organic solvents. |
| format |
บทความวารสาร |
| author |
Hamzeh Kiyani Heshmat Allah Samimi |
| spellingShingle |
Hamzeh Kiyani Heshmat Allah Samimi Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium |
| author_facet |
Hamzeh Kiyani Heshmat Allah Samimi |
| author_sort |
Hamzeh Kiyani |
| title |
Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium |
| title_short |
Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium |
| title_full |
Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium |
| title_fullStr |
Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium |
| title_full_unstemmed |
Nickel-catalyzed One-pot, Three-component Synthesis of 3,4-Disubstituted Isoxazole-5(4H)-ones in Aqueous Medium |
| title_sort |
nickel-catalyzed one-pot, three-component synthesis of 3,4-disubstituted isoxazole-5(4h)-ones in aqueous medium |
| publisher |
Science Faculty of Chiang Mai University |
| publishDate |
2019 |
| url |
http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=8289 http://cmuir.cmu.ac.th/jspui/handle/6653943832/63929 |
| _version_ |
1681425986734784512 |