Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime

The aim of this study was, to analyze and compare the composition of volatile constituents in the essential oils from the peel of Citrus aurantifolia L. grown in three different regions of Oman and to investigate their antioxidant and antibacterial potential. The essential oil from the fresh peels w...

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Main Authors: Amwaj Mohammed Al-Breiki, Huda Mubarak Al-Brashdi, Jamal Nasser Al-Sabahi, Shah Alam Khan
Format: บทความวารสาร
Language:English
Published: Science Faculty of Chiang Mai University 2019
Online Access:http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=9318
http://cmuir.cmu.ac.th/jspui/handle/6653943832/64154
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Institution: Chiang Mai University
Language: English
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spelling th-cmuir.6653943832-641542019-05-07T09:59:50Z Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime Amwaj Mohammed Al-Breiki Huda Mubarak Al-Brashdi Jamal Nasser Al-Sabahi Shah Alam Khan The aim of this study was, to analyze and compare the composition of volatile constituents in the essential oils from the peel of Citrus aurantifolia L. grown in three different regions of Oman and to investigate their antioxidant and antibacterial potential. The essential oil from the fresh peels was isolated by hydro-distillation method and chemical composition analysis of oils was carried out by Gas chromatography–Mass spectrometry (GC-MS). The antioxidant activity was investigated by a non enzymatic free radical scavenging method while antibacterial activity was tested against gram positive and gram negative bacteria by disc diffusion method. Molecular docking studies were also carried out to probe the mechanism of antioxidant activity. GC-MS analysis indicated variation in content and composition of chemical constituents in the peel oils. Limonene was found to be the major volatile constituent thus establishing lime peel oil as limonene chemotype. The peel essential oils of C. aurantifolia showed moderate antioxidant and antibacterial activitities. Molecular docking studies indicated α-farnesene to have better binding affinity for Xanthine oxidoreductase in comparison to limonene and pinene. Further studies are needed to develop the lime peel oil as an antimicrobial preservative and an alternative source of natural antioxidant(s). 2019-05-07T09:59:50Z 2019-05-07T09:59:50Z 2018 บทความวารสาร 0125-2526 http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=9318 http://cmuir.cmu.ac.th/jspui/handle/6653943832/64154 Eng Science Faculty of Chiang Mai University
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description The aim of this study was, to analyze and compare the composition of volatile constituents in the essential oils from the peel of Citrus aurantifolia L. grown in three different regions of Oman and to investigate their antioxidant and antibacterial potential. The essential oil from the fresh peels was isolated by hydro-distillation method and chemical composition analysis of oils was carried out by Gas chromatography–Mass spectrometry (GC-MS). The antioxidant activity was investigated by a non enzymatic free radical scavenging method while antibacterial activity was tested against gram positive and gram negative bacteria by disc diffusion method. Molecular docking studies were also carried out to probe the mechanism of antioxidant activity. GC-MS analysis indicated variation in content and composition of chemical constituents in the peel oils. Limonene was found to be the major volatile constituent thus establishing lime peel oil as limonene chemotype. The peel essential oils of C. aurantifolia showed moderate antioxidant and antibacterial activitities. Molecular docking studies indicated α-farnesene to have better binding affinity for Xanthine oxidoreductase in comparison to limonene and pinene. Further studies are needed to develop the lime peel oil as an antimicrobial preservative and an alternative source of natural antioxidant(s).
format บทความวารสาร
author Amwaj Mohammed Al-Breiki
Huda Mubarak Al-Brashdi
Jamal Nasser Al-Sabahi
Shah Alam Khan
spellingShingle Amwaj Mohammed Al-Breiki
Huda Mubarak Al-Brashdi
Jamal Nasser Al-Sabahi
Shah Alam Khan
Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
author_facet Amwaj Mohammed Al-Breiki
Huda Mubarak Al-Brashdi
Jamal Nasser Al-Sabahi
Shah Alam Khan
author_sort Amwaj Mohammed Al-Breiki
title Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
title_short Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
title_full Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
title_fullStr Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
title_full_unstemmed Comparative GC-MS Analysis, In-vitro Antioxidant and Antimicrobial Activities of the Essential Oils Isolated from the Peel of Omani Lime
title_sort comparative gc-ms analysis, in-vitro antioxidant and antimicrobial activities of the essential oils isolated from the peel of omani lime
publisher Science Faculty of Chiang Mai University
publishDate 2019
url http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=9318
http://cmuir.cmu.ac.th/jspui/handle/6653943832/64154
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