Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii
Two new dimeric carbazole alkaloids, clausenawallines A and B, were isolated from the roots of Clausena wallichii. Their structures were elucidated by spectroscopic methods. Clausenawalline A was evaluated for its biological activities [anti-malaria (IC50 2.46 μg/mL), anti-TB (MIC 12.50 μg/mL)] and...
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th-cmuir.6653943832-65342014-08-30T03:24:19Z Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii Maneerat W. Ritthiwigrom T. Cheenpracha S. Prawat U. Laphookhieo S. Two new dimeric carbazole alkaloids, clausenawallines A and B, were isolated from the roots of Clausena wallichii. Their structures were elucidated by spectroscopic methods. Clausenawalline A was evaluated for its biological activities [anti-malaria (IC50 2.46 μg/mL), anti-TB (MIC 12.50 μg/mL)] and cytotoxicity against three human cancer cell lines [KB (IC 50 7.87 μg/mL), MCF7 (IC50 25.43 μg/mL), and NCI-H187 (IC50 10.97 μg/mL)]. © 2011 Elsevier Ltd. All rights reserved. 2014-08-30T03:24:19Z 2014-08-30T03:24:19Z 2011 Article 404039 10.1016/j.tetlet.2011.04.064 TELEA http://www.scopus.com/inward/record.url?eid=2-s2.0-79957607206&partnerID=40&md5=bffa2ce3f50d32afc01d0537a0a93cb8 http://cmuir.cmu.ac.th/handle/6653943832/6534 English |
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Two new dimeric carbazole alkaloids, clausenawallines A and B, were isolated from the roots of Clausena wallichii. Their structures were elucidated by spectroscopic methods. Clausenawalline A was evaluated for its biological activities [anti-malaria (IC50 2.46 μg/mL), anti-TB (MIC 12.50 μg/mL)] and cytotoxicity against three human cancer cell lines [KB (IC 50 7.87 μg/mL), MCF7 (IC50 25.43 μg/mL), and NCI-H187 (IC50 10.97 μg/mL)]. © 2011 Elsevier Ltd. All rights reserved. |
| format |
Article |
| author |
Maneerat W. Ritthiwigrom T. Cheenpracha S. Prawat U. Laphookhieo S. |
| spellingShingle |
Maneerat W. Ritthiwigrom T. Cheenpracha S. Prawat U. Laphookhieo S. Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii |
| author_facet |
Maneerat W. Ritthiwigrom T. Cheenpracha S. Prawat U. Laphookhieo S. |
| author_sort |
Maneerat W. |
| title |
Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii |
| title_short |
Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii |
| title_full |
Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii |
| title_fullStr |
Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii |
| title_full_unstemmed |
Clausenawallines A and B, two new dimeric carbazole alkaloids from the roots of Clausena wallichii |
| title_sort |
clausenawallines a and b, two new dimeric carbazole alkaloids from the roots of clausena wallichii |
| publishDate |
2014 |
| url |
http://www.scopus.com/inward/record.url?eid=2-s2.0-79957607206&partnerID=40&md5=bffa2ce3f50d32afc01d0537a0a93cb8 http://cmuir.cmu.ac.th/handle/6653943832/6534 |
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1681420631840653312 |