Human platelet lysate as an alternative to fetal bovine serum for culture and endothelial differentiation of human amniotic fluid mesenchymal stem cells

• Main Authors: Waleephan Tancharoen, Sirinda Aungsuchawan, Peraphan Pothacharoen, Kanokkan Bumroongkit, Chaniporn Puaninta, Nathaporn Pangjaidee, Suteera Narakornsak, Runchana Markmee, Tanongsak Laowanitwattana, Chawapon Thaojamnong
• Format: Journal
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066160234&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/65369
• Institution: Chiang Mai University

Human amniotic fluid (hAF) mesenchymal stem cells (MSCs) are commonly cultured in medium containing FBS. However, there are concerns about using animal serum in therapeutic applications due to the potential for immunogenic reactions and the risk of transmission of pathogens. For safety reasons, huma...