Morphology of the human aorta and age-related changes: Anatomical facts

© 2019 Anatomy & Cell Biology. Aorta is the largest artery in the human body. Its starting point is the aortic orifice of the aortic valve and it terminates at the level of the fourth lumbar vertebra. The main function of the aorta is to transport oxygenated blood to supply all the organs and...

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Main Authors: Pornhatai Komutrattananont, Pasuk Mahakkanukrauh, Srijit Das
Format: Journal
Published: 2019
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/65374
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-653742019-08-05T04:42:15Z Morphology of the human aorta and age-related changes: Anatomical facts Pornhatai Komutrattananont Pasuk Mahakkanukrauh Srijit Das Biochemistry, Genetics and Molecular Biology Medicine Neuroscience © 2019 Anatomy & Cell Biology. Aorta is the largest artery in the human body. Its starting point is the aortic orifice of the aortic valve and it terminates at the level of the fourth lumbar vertebra. The main function of the aorta is to transport oxygenated blood to supply all the organs and cells. With advancing age, the structure and hence the function show progressive changes. Various changes in the aortic morphology include the luminal diameter of aorta, whole length of the aorta, thickness, the microstructural components also change, and these include collagen, elastin and smooth muscle cells. In addition, the dimensions of all segments of the aorta increase with age in both sexes. Since age is a major risk factor for degenerative change and diseases affecting the aorta, understanding the detailed anatomy of the aorta may provide essential information concerning the age-associated process of the aorta. Knowledge of the morphological changes in the aorta is also important for future clinical therapies pertaining to aortic disease. Additionally, the information regarding the structural changes with age may be applied for age determination. This review describes the overview of the anatomy of the aorta, age related changes in the morphology of the aorta and aortic diseases. 2019-08-05T04:32:18Z 2019-08-05T04:32:18Z 2019-06-01 Journal 20933673 20933665 2-s2.0-85069047748 10.5115/acb.2019.52.2.109 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85069047748&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/65374
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Neuroscience
Pornhatai Komutrattananont
Pasuk Mahakkanukrauh
Srijit Das
Morphology of the human aorta and age-related changes: Anatomical facts
description © 2019 Anatomy & Cell Biology. Aorta is the largest artery in the human body. Its starting point is the aortic orifice of the aortic valve and it terminates at the level of the fourth lumbar vertebra. The main function of the aorta is to transport oxygenated blood to supply all the organs and cells. With advancing age, the structure and hence the function show progressive changes. Various changes in the aortic morphology include the luminal diameter of aorta, whole length of the aorta, thickness, the microstructural components also change, and these include collagen, elastin and smooth muscle cells. In addition, the dimensions of all segments of the aorta increase with age in both sexes. Since age is a major risk factor for degenerative change and diseases affecting the aorta, understanding the detailed anatomy of the aorta may provide essential information concerning the age-associated process of the aorta. Knowledge of the morphological changes in the aorta is also important for future clinical therapies pertaining to aortic disease. Additionally, the information regarding the structural changes with age may be applied for age determination. This review describes the overview of the anatomy of the aorta, age related changes in the morphology of the aorta and aortic diseases.
format Journal
author Pornhatai Komutrattananont
Pasuk Mahakkanukrauh
Srijit Das
author_facet Pornhatai Komutrattananont
Pasuk Mahakkanukrauh
Srijit Das
author_sort Pornhatai Komutrattananont
title Morphology of the human aorta and age-related changes: Anatomical facts
title_short Morphology of the human aorta and age-related changes: Anatomical facts
title_full Morphology of the human aorta and age-related changes: Anatomical facts
title_fullStr Morphology of the human aorta and age-related changes: Anatomical facts
title_full_unstemmed Morphology of the human aorta and age-related changes: Anatomical facts
title_sort morphology of the human aorta and age-related changes: anatomical facts
publishDate 2019
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85069047748&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/65374
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