Cave actinobacteria as producers of bioactive metabolites

Copyright © 2019 Rangseekaew and Pathom-aree. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited an...

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Main Authors: Pharada Rangseekaew, Wasu Pathom-Aree
Format: Journal
Published: 2019
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/65656
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-656562019-08-05T04:41:33Z Cave actinobacteria as producers of bioactive metabolites Pharada Rangseekaew Wasu Pathom-Aree Immunology and Microbiology Medicine Copyright © 2019 Rangseekaew and Pathom-aree. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Recently, there is an urgent need for new drugs due to the emergence of drug resistant pathogenic microorganisms and new infectious diseases. Members of phylum Actinobacteria are promising source of bioactive compounds notably antibiotics. The search for such new compounds has shifted to extreme or underexplored environments to increase the possibility of discovery. Cave ecosystems have attracted interest of the research community because of their unique characteristics and the microbiome residing inside including actinobacteria. At the time of writing, 47 species in 30 genera of actinobacteria were reported from cave and cave related habitats. Novel and promising bioactive compounds have been isolated and characterized. This mini-review focuses on the diversity of cultivable actinobacteria in cave and cave-related environments, and their bioactive metabolites from 1999 to 2018. 2019-08-05T04:38:20Z 2019-08-05T04:38:20Z 2019-01-01 Journal 1664302X 2-s2.0-85066487348 10.3389/fmicb.2019.00387 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066487348&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/65656
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Immunology and Microbiology
Medicine
spellingShingle Immunology and Microbiology
Medicine
Pharada Rangseekaew
Wasu Pathom-Aree
Cave actinobacteria as producers of bioactive metabolites
description Copyright © 2019 Rangseekaew and Pathom-aree. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Recently, there is an urgent need for new drugs due to the emergence of drug resistant pathogenic microorganisms and new infectious diseases. Members of phylum Actinobacteria are promising source of bioactive compounds notably antibiotics. The search for such new compounds has shifted to extreme or underexplored environments to increase the possibility of discovery. Cave ecosystems have attracted interest of the research community because of their unique characteristics and the microbiome residing inside including actinobacteria. At the time of writing, 47 species in 30 genera of actinobacteria were reported from cave and cave related habitats. Novel and promising bioactive compounds have been isolated and characterized. This mini-review focuses on the diversity of cultivable actinobacteria in cave and cave-related environments, and their bioactive metabolites from 1999 to 2018.
format Journal
author Pharada Rangseekaew
Wasu Pathom-Aree
author_facet Pharada Rangseekaew
Wasu Pathom-Aree
author_sort Pharada Rangseekaew
title Cave actinobacteria as producers of bioactive metabolites
title_short Cave actinobacteria as producers of bioactive metabolites
title_full Cave actinobacteria as producers of bioactive metabolites
title_fullStr Cave actinobacteria as producers of bioactive metabolites
title_full_unstemmed Cave actinobacteria as producers of bioactive metabolites
title_sort cave actinobacteria as producers of bioactive metabolites
publishDate 2019
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85066487348&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/65656
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