Brief Report: Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cutoff for a Point-of-Care Test

• Main Authors: Monica Gandhi, Peter Bacchetti, Matthew A. Spinelli, Hideaki Okochi, Jared M. Baeten, Oraphan Siriprakaisil, Virat Klinbuayaem, Warren C. Rodrigues, Guohong Wang, Michael Vincent, Tim R. Cressey, Paul K. Drain
• Format: Journal
• Published: 2019
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85064721305&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/65760
• Institution: Chiang Mai University

BACKGROUND: Current pharmacologic adherence monitoring for antiretrovirals involves expensive, labor-intensive liquid chromatography/tandem mass spectrometry (LC-MS/MS)-based methods. Antibody-based assays can monitor and support adherence in real time. We developed a tenofovir (TFV)-based immunoass...