Biotransformation of natural compounds. Oxido-reduction of Sch-642305 by Aspergillus ochraceus ATCC 1009

• Main Authors: Adelin E., Servy C., Cortial S., Levaique H., Gallard J.F., Martin M.-T., Retailleau P., Bussaban B., Lumyong S., Ouazzani J.
• Format: Article
• Language: English
• Published: 2014
• Online Access: http://www.scopus.com/inward/record.url?eid=2-s2.0-79953278003&partnerID=40&md5=43ba72765d39b6386d6e7b0029dad238; http://cmuir.cmu.ac.th/handle/6653943832/6577
• Institution: Chiang Mai University

Sch-642305 is the major compound produced by the endophytic fungi Phomopsis sp. CMU-LMA. Incubation of Sch-642305 with Aspergillus ochraceus ATCC 1009 resting cells leads to three new derivatives through an oxido-reduction of the six-membered ring of the molecule. Reduction of the double bound leads...