Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses

© 2019 International Federation of Gynecology and Obstetrics Objective: To compare the diagnostic accuracy of International Ovarian Tumor Analysis (IOTA) simple rules and risk of malignancy index (RMI 1/RMI 2) scoring to discriminate between benign and malignant adnexal masses. Methods: Secondary an...

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Main Authors: Rapeepat Auekitrungrueng, Dangcheewan Tinnangwattana, Charuwan Tantipalakorn, Cholaros Charoenratana, Thitikarn Lerthiranwong, Chanane Wanapirak, Theera Tongsong
Format: Journal
Published: 2019
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/65796
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-657962019-08-05T04:41:25Z Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses Rapeepat Auekitrungrueng Dangcheewan Tinnangwattana Charuwan Tantipalakorn Cholaros Charoenratana Thitikarn Lerthiranwong Chanane Wanapirak Theera Tongsong Medicine © 2019 International Federation of Gynecology and Obstetrics Objective: To compare the diagnostic accuracy of International Ovarian Tumor Analysis (IOTA) simple rules and risk of malignancy index (RMI 1/RMI 2) scoring to discriminate between benign and malignant adnexal masses. Methods: Secondary analysis of a cohort of patients scheduled for surgery for adnexal masses in a tertiary center between April 2010 and March 2018. Ultrasound examinations were performed by general gynecologists within 24 hours prior to surgery to evaluate sonographic features. Demographic data and preoperative CA 125 levels were recorded. IOTA rules and RMI scoring were applied to predict malignancy and prospectively recorded. Final diagnosis was based on pathological or intraoperative diagnosis. Results: A total of 479 masses met the inclusion criteria and were retrieved from the database: 334 (69.7%) benign and 145 (30.3%) malignant. IOTA rules could be applied to 392 (81.8%) masses and were inconclusive in 87 (18.2%). Sensitivity and specificity of IOTA rules (83.8% and 92.0%, respectively) were significantly higher than RMI 1 (77.2% and 86.8%, respectively) and RMI 2 (82.1% and 82.6%, respectively). Conclusion: IOTA simple rules had higher diagnostic accuracy compared with RMI to discriminate between benign and malignant adnexal masses; however, nearly 20% of IOTA results were inconclusive and needed expert consultation. 2019-08-05T04:41:25Z 2019-08-05T04:41:25Z 2019-01-01 Journal 18793479 00207292 2-s2.0-85068648876 10.1002/ijgo.12891 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068648876&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/65796
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Rapeepat Auekitrungrueng
Dangcheewan Tinnangwattana
Charuwan Tantipalakorn
Cholaros Charoenratana
Thitikarn Lerthiranwong
Chanane Wanapirak
Theera Tongsong
Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
description © 2019 International Federation of Gynecology and Obstetrics Objective: To compare the diagnostic accuracy of International Ovarian Tumor Analysis (IOTA) simple rules and risk of malignancy index (RMI 1/RMI 2) scoring to discriminate between benign and malignant adnexal masses. Methods: Secondary analysis of a cohort of patients scheduled for surgery for adnexal masses in a tertiary center between April 2010 and March 2018. Ultrasound examinations were performed by general gynecologists within 24 hours prior to surgery to evaluate sonographic features. Demographic data and preoperative CA 125 levels were recorded. IOTA rules and RMI scoring were applied to predict malignancy and prospectively recorded. Final diagnosis was based on pathological or intraoperative diagnosis. Results: A total of 479 masses met the inclusion criteria and were retrieved from the database: 334 (69.7%) benign and 145 (30.3%) malignant. IOTA rules could be applied to 392 (81.8%) masses and were inconclusive in 87 (18.2%). Sensitivity and specificity of IOTA rules (83.8% and 92.0%, respectively) were significantly higher than RMI 1 (77.2% and 86.8%, respectively) and RMI 2 (82.1% and 82.6%, respectively). Conclusion: IOTA simple rules had higher diagnostic accuracy compared with RMI to discriminate between benign and malignant adnexal masses; however, nearly 20% of IOTA results were inconclusive and needed expert consultation.
format Journal
author Rapeepat Auekitrungrueng
Dangcheewan Tinnangwattana
Charuwan Tantipalakorn
Cholaros Charoenratana
Thitikarn Lerthiranwong
Chanane Wanapirak
Theera Tongsong
author_facet Rapeepat Auekitrungrueng
Dangcheewan Tinnangwattana
Charuwan Tantipalakorn
Cholaros Charoenratana
Thitikarn Lerthiranwong
Chanane Wanapirak
Theera Tongsong
author_sort Rapeepat Auekitrungrueng
title Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
title_short Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
title_full Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
title_fullStr Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
title_full_unstemmed Comparison of the diagnostic accuracy of International Ovarian Tumor Analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
title_sort comparison of the diagnostic accuracy of international ovarian tumor analysis simple rules and the risk of malignancy index to discriminate between benign and malignant adnexal masses
publishDate 2019
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85068648876&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/65796
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