Efavirenz pharmacokinetics during pregnancy and infant washout

• Main Authors: Regis Kreitchmann, Stein Schalkwijk, Brookie Best, Jiajia Wang, Angela Colbers, Alice Stek, David Shapiro, Tim Cressey, Mark Mirochnick, David Burger
• Format: Journal
• Published: 2019
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85065855757&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/65839
• Institution: Chiang Mai University

©2019 International Medical Press Background: Limited data exist on efavirenz pharmacokinetics in HIV-positive pregnant women and neonatal washout. Methods: HIV-infected pregnant women receiving 600 mg efavirenz once daily had intensive steady-state 24-h pharmacokinetics profiles during the second t...