Optimizations of Hydroxyl Terminated Polymerization of Mannose Tricyclic Orthoester Toward Ready-to-use Lipomannan Backbone

• Main Authors: Harin Leelayuwapan, Somsak Ruchirawat, Siwarutt Boonyarattanakalin
• Language: English
• Published: Science Faculty of Chiang Mai University 2019
• Subjects: polymannan; carbohydrate; Mycobacterium tuberculosis (Mtb); lipomannan (LM)
• Online Access: http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=6345; http://cmuir.cmu.ac.th/jspui/handle/6653943832/66066
• Institution: Chiang Mai University

Throughout the life cycle of mycobacterium tuberculosis (Mtb), its survival critically depends on its interactions with mammalian host cells. Therefore, in order to have better treatments for and preventions of tuberculosis (TB), it is important to understand the biological activity of the Mtb surfa...