Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293

Ophiobolides, Polyketides Isolated from Ophiobolus sp. KTC 2293

Three new polyketides, ophiobolides A, B, and C, were isolated from the culture broth of Ophiobolus sp. KTC 2293 along with structurally related achaetolide. The structures of these polyketides were elucidated on the basis of NMR and MS analyses. Ophiobolide B showed a weak antifungal activity again...

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Bibliographic Details
Main Authors: Wilanfranco C. Tayone, Kazuaki Tanaka, Noboru Takada
Language:English
Published: Science Faculty of Chiang Mai University 2019
Subjects:
ophiobolide
polyketides
Ophiobolus
structural elucidation
antifungal activity
Online Access:http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=6806
http://cmuir.cmu.ac.th/jspui/handle/6653943832/66110
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Institution: Chiang Mai University
Language: English
Description
Summary:Three new polyketides, ophiobolides A, B, and C, were isolated from the culture broth of Ophiobolus sp. KTC 2293 along with structurally related achaetolide. The structures of these polyketides were elucidated on the basis of NMR and MS analyses. Ophiobolide B showed a weak antifungal activity against Cochliobolus miyabeanus.

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