Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor
Schizophyllum commune, a basidiomycetes species, exhibited the anti-fungal properties by producing several bioactive compounds during secondary metabolism. One flavonoid fraction, named 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- (DDMP), has received much attention for its antifungal activity...
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2019
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th-cmuir.6653943832-661242019-08-21T09:18:22Z Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor Yi Peng, Teoh Mashitah, Mat Don Schizophyllum commune Total flavonoid 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- (DDMP) Bubble column bioreactor Temperature High performance liquid chromatography (HPLC) Schizophyllum commune, a basidiomycetes species, exhibited the anti-fungal properties by producing several bioactive compounds during secondary metabolism. One flavonoid fraction, named 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- (DDMP), has received much attention for its antifungal activity toward wood-degrading fungi of rubberwood. In the present study, the effect of temperature on the growth and bioactive compound production by Schizophyllum commune was investigated in a bubble column bioreactor. Results revealed that the highest production of biomass (35.11±0.12 g/L), total flavonoids (1.328±0.007 µg QE/mg sample), and DDMP (1.278±0.005 µg/mg sample) were achieved in the culture grown at 30 oC. The separation of crude extract was studied using a high performance liquid chromatography (HPLC) system equipped with a Zorbax XDB C18 column. 2019-08-21T09:18:22Z 2019-08-21T09:18:22Z 2015 Chiang Mai Journal of Science 42, 3 (July 2015), 539 - 548 0125-2526 http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=5947 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66124 Eng Science Faculty of Chiang Mai University |
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Schizophyllum commune Total flavonoid 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- (DDMP) Bubble column bioreactor Temperature High performance liquid chromatography (HPLC) |
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Schizophyllum commune Total flavonoid 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- (DDMP) Bubble column bioreactor Temperature High performance liquid chromatography (HPLC) Yi Peng, Teoh Mashitah, Mat Don Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
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Schizophyllum commune, a basidiomycetes species, exhibited the anti-fungal properties by producing several bioactive compounds during secondary metabolism. One flavonoid fraction, named 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- (DDMP), has received much attention for its antifungal activity toward wood-degrading fungi of rubberwood. In the present study, the effect of temperature on the growth and bioactive compound production by Schizophyllum commune was investigated in a bubble column bioreactor. Results revealed that the highest production of biomass (35.11±0.12 g/L), total flavonoids (1.328±0.007 µg QE/mg sample), and DDMP (1.278±0.005 µg/mg sample) were achieved in the culture grown at 30 oC. The separation of crude extract was studied using a high performance liquid chromatography (HPLC) system equipped with a Zorbax XDB C18 column. |
author |
Yi Peng, Teoh Mashitah, Mat Don |
author_facet |
Yi Peng, Teoh Mashitah, Mat Don |
author_sort |
Yi Peng, Teoh |
title |
Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
title_short |
Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
title_full |
Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
title_fullStr |
Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
title_full_unstemmed |
Effect of temperature on Schizophyllum commune growth and 4H-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
title_sort |
effect of temperature on schizophyllum commune growth and 4h-pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- production using a bubble column bioreactor |
publisher |
Science Faculty of Chiang Mai University |
publishDate |
2019 |
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http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=5947 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66124 |
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