A Simple Method Based on One Phase Measurement for Determination of the Octanol-Water Partition Coefficient of Drugs
The octanol-water partition coefficient (Pow) is widely used to assessment of lipophilicity of drug. The Pow can be measured by determining the ratio of the concentration of the drug in octanol to its concentration in water at equilibrium. In the standard method, two calibration curves are require...
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| Main Authors: | , , , |
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| Language: | English |
| Published: |
Science Faculty of Chiang Mai University
2019
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| Subjects: | |
| Online Access: | http://it.science.cmu.ac.th/ejournal/dl.php?journal_id=5957 http://cmuir.cmu.ac.th/jspui/handle/6653943832/66140 |
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| Institution: | Chiang Mai University |
| Language: | English |