Glycopentaphyllone: The first isolation of hydroperoxyquinolone from the fruits of Glycosmis pentaphylla

A new hydroperoxyquinolone alkaloid, glycopentaphyllone (1), along with nine compounds (2-10), was isolated from the fruits of Glycosmis pentaphylla. Their structures were elucidated on the basis of spectroscopic methods. The absolute configuration of glycopentaphyllone at C-2′ was established as S-...

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Bibliographic Details
Main Authors: Sripisut T., Ritthiwigrom T., Promgool T., Yossathera K., Deachathai S., Phakhodee W., Cheenpracha S., Laphookhieo S.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84860530411&partnerID=40&md5=0dd42f2117860d5c337a630c58e06780
http://cmuir.cmu.ac.th/handle/6653943832/6653
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Institution: Chiang Mai University
Language: English
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Summary:A new hydroperoxyquinolone alkaloid, glycopentaphyllone (1), along with nine compounds (2-10), was isolated from the fruits of Glycosmis pentaphylla. Their structures were elucidated on the basis of spectroscopic methods. The absolute configuration of glycopentaphyllone at C-2′ was established as S-configuration by applying Mosher's method. In addition, the completed assignments of 13C NMR as well as 2D NMR spectral data of compound 5 were reported herein for the first time. Also, all isolates were evaluated for antibacterial activity against Escherichia coli TISTR 780, Salmonella typhimurium TISTR 292, Staphylococcus aureus TISTR 1466, and Methicillin-resistant S. aureus SK1. © 2012 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.