Impact of Estimated Pre-Exposure Prophylaxis (PrEP) Adherence Patterns on Bone Mineral Density in a Large PrEP Demonstration Project

• Main Authors: Matthew A. Spinelli, David V. Glidden, Peter L. Anderson, Monica Gandhi, Vanessa M. McMahan, Patricia Defechereux, Mauro Schechter, Valdiléa G. Veloso, Suwat Chariyalertsak, Juan V. Guanira, Linda Gail Bekker, Susan P. Buchbinder, Robert M. Grant
• Format: Journal
• Published: 2019
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85071997499&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/66679
• Institution: Chiang Mai University

Bone mineral density (BMD) declines due to tenofovir-containing pre-exposure prophylaxis (PrEP) have varied among PrEP demonstration projects, potentially related to variable adherence. Characterization of BMD changes in highly adherent individuals, estimated via tenofovir-diphosphate (TFV-DP) level...