Next-generation of targeted AAVP vectors for systemic transgene delivery against cancer

• Main Authors: Keittisak Suwan, Teerapong Yata, Sajee Waramit, Justyna M. Przystal, Charlotte A. Stoneham, Kaoutar Bentayebi, Paladd Asavarut, Aitthiphon Chongchai, Peraphan Pothachareon, Koon Yang Lee, Supachai Topanurak, Tracey L. Smith, Juri G. Gelovani, Richard L. Sidman, Renata Pasqualini, Wadih Arap, Amin Hajitou
• Format: Journal
• Published: 2019
• Subjects: Multidisciplinary
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85072058541&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/66748
• Institution: Chiang Mai University

Copyright © 2019 the Author(s). Published by PNAS. Bacteriophage (phage) have attractive advantages as delivery systems compared with mammalian viruses, but have been considered poor vectors because they lack evolved strategies to confront and overcome mammalian cell barriers to infective agents. We...