Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities

A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data....

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Main Authors: Nayyatip S., Thaichana P., Buayairaksa M., Tuntiwechapikul W., Meepowpan P., Nuntasaen N., Pompimon W.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84860116503&partnerID=40&md5=a045402327748bdd86971e6e733f3293
http://www.ncbi.nlm.nih.gov/pubmed/22606026
http://cmuir.cmu.ac.th/handle/6653943832/6704
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spelling th-cmuir.6653943832-67042014-08-30T03:51:08Z Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities Nayyatip S. Thaichana P. Buayairaksa M. Tuntiwechapikul W. Meepowpan P. Nuntasaen N. Pompimon W. A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors. 2014-08-30T03:51:08Z 2014-08-30T03:51:08Z 2012 Article 14220067 10.3390/ijms13045010 http://www.scopus.com/inward/record.url?eid=2-s2.0-84860116503&partnerID=40&md5=a045402327748bdd86971e6e733f3293 http://www.ncbi.nlm.nih.gov/pubmed/22606026 http://cmuir.cmu.ac.th/handle/6653943832/6704 English
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
language English
description A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively. © 2012 by the authors.
format Article
author Nayyatip S.
Thaichana P.
Buayairaksa M.
Tuntiwechapikul W.
Meepowpan P.
Nuntasaen N.
Pompimon W.
spellingShingle Nayyatip S.
Thaichana P.
Buayairaksa M.
Tuntiwechapikul W.
Meepowpan P.
Nuntasaen N.
Pompimon W.
Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
author_facet Nayyatip S.
Thaichana P.
Buayairaksa M.
Tuntiwechapikul W.
Meepowpan P.
Nuntasaen N.
Pompimon W.
author_sort Nayyatip S.
title Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_short Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_full Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_fullStr Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_full_unstemmed Aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
title_sort aristolactam-type alkaloids from orophea enterocarpa and their cytotoxicities
publishDate 2014
url http://www.scopus.com/inward/record.url?eid=2-s2.0-84860116503&partnerID=40&md5=a045402327748bdd86971e6e733f3293
http://www.ncbi.nlm.nih.gov/pubmed/22606026
http://cmuir.cmu.ac.th/handle/6653943832/6704
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