The role of d-galactose in the aging heart and brain

© 2019 Elsevier Inc. All rights reserved. Aging is an inevitable, complex biological process caused by a variety of factors including both genetic and environmental influences. It is one of the prime risk factors for the advancement of many pathological conditions such as cardiovascular diseases and...

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Main Authors: Cherry Bo-Htay, Thazin Shwe, Siriporn C. Chattipakorn, Nipon Chattipakorn
Format: Book
Published: 2020
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081906753&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/67537
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-675372020-04-02T15:06:01Z The role of d-galactose in the aging heart and brain Cherry Bo-Htay Thazin Shwe Siriporn C. Chattipakorn Nipon Chattipakorn Agricultural and Biological Sciences Engineering © 2019 Elsevier Inc. All rights reserved. Aging is an inevitable, complex biological process caused by a variety of factors including both genetic and environmental influences. It is one of the prime risk factors for the advancement of many pathological conditions such as cardiovascular diseases and neurodegenerative disorders. Numerous animal models have been used to add to our understanding of the aging process, to inform therapeutic interventions, and to limit the aging effects on various organs. Of these models the d-galactose-induced aging model is the most commonly used as a mimetic aging model. Despite the frequent use of this model, actually, how d-galactose accelerates cardiac and brain aging remains unclear. Currently, hyperbaric oxygen therapy (HBOT) is used to treat neurodegeneration and brain injury. This chapter comprehensively summarizes recent results from d-galactose treatment in both in vitro and in vivo cardiac and brain aging experiments and the different aspects of therapeutic interventions, in particular HBOT. 2020-04-02T14:55:18Z 2020-04-02T14:55:18Z 2019-01-01 Book 2-s2.0-85081906753 10.1016/B978-0-12-849886-6.00022-7 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081906753&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/67537
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Agricultural and Biological Sciences
Engineering
spellingShingle Agricultural and Biological Sciences
Engineering
Cherry Bo-Htay
Thazin Shwe
Siriporn C. Chattipakorn
Nipon Chattipakorn
The role of d-galactose in the aging heart and brain
description © 2019 Elsevier Inc. All rights reserved. Aging is an inevitable, complex biological process caused by a variety of factors including both genetic and environmental influences. It is one of the prime risk factors for the advancement of many pathological conditions such as cardiovascular diseases and neurodegenerative disorders. Numerous animal models have been used to add to our understanding of the aging process, to inform therapeutic interventions, and to limit the aging effects on various organs. Of these models the d-galactose-induced aging model is the most commonly used as a mimetic aging model. Despite the frequent use of this model, actually, how d-galactose accelerates cardiac and brain aging remains unclear. Currently, hyperbaric oxygen therapy (HBOT) is used to treat neurodegeneration and brain injury. This chapter comprehensively summarizes recent results from d-galactose treatment in both in vitro and in vivo cardiac and brain aging experiments and the different aspects of therapeutic interventions, in particular HBOT.
format Book
author Cherry Bo-Htay
Thazin Shwe
Siriporn C. Chattipakorn
Nipon Chattipakorn
author_facet Cherry Bo-Htay
Thazin Shwe
Siriporn C. Chattipakorn
Nipon Chattipakorn
author_sort Cherry Bo-Htay
title The role of d-galactose in the aging heart and brain
title_short The role of d-galactose in the aging heart and brain
title_full The role of d-galactose in the aging heart and brain
title_fullStr The role of d-galactose in the aging heart and brain
title_full_unstemmed The role of d-galactose in the aging heart and brain
title_sort role of d-galactose in the aging heart and brain
publishDate 2020
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85081906753&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/67537
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