Dicentrine potentiates TNF-α-induced apoptosis and suppresses invasion of a549 lung adenocarcinoma cells via modulation of nf-κb and ap-1 activation

• Main Authors: Chanatip Ooppachai, Pornngarm Limtrakul, Supachai Yodkeeree
• Format: Journal
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85074969415&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/67603
• Institution: Chiang Mai University

© 2019 by the authors. Numerous studies have indicated that tumor necrosis factor-alpha (TNF-α) could induce cancer cell survival and metastasis via activation of transcriptional activity of NF-κB and AP-1. Therefore, the inhibition of TNF-α-induced NF-κB and AP-1 activity has been considered in the...