Tricycloalternarene derivatives from the endophytic fungus Guignardia bidwellii PSU-G11

Four new tricycloalternarene derivatives, guignarenones A-D (1-4), along with known (6S,9R)-vomifoliol were isolated from the endophytic fungus Guignardia bidwellii PSU-G11. Their structures were determined on the basis of spectroscopic data. The absolute configurations in 1 were assigned using a co...

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Bibliographic Details
Main Authors: Sommart U., Rukachaisirikul V., Trisuwan K., Tadpetch K., Phongpaichit S., Preedanon S., Sakayaroj J.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-84856713796&partnerID=40&md5=b73e161f83a39fb5ad775a03303fab18
http://cmuir.cmu.ac.th/handle/6653943832/6831
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Institution: Chiang Mai University
Language: English
Description
Summary:Four new tricycloalternarene derivatives, guignarenones A-D (1-4), along with known (6S,9R)-vomifoliol were isolated from the endophytic fungus Guignardia bidwellii PSU-G11. Their structures were determined on the basis of spectroscopic data. The absolute configurations in 1 were assigned using a combination of the modified Mosher's method and NOEDIFF data. Compound 1 displayed mild cytotoxic activity against oral cavity cancer and African green monkey kidney fibroblast (Vero) cell lines. © 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.