Enhanced production of infectious particles by adaptive modulation of C-prM processing and C-C interaction during propagation of dengue pseudoinfectious virus in stable CprME-expressing cells

• Main Authors: Sutha Sangiambut, Chatpong Pethrak, Chainarong Anupap, Parichat Ninnabkaew, Charuphan Kongsanthia, Natcha Promphet, Suwipa Chaiyaloom, Adisak Songjaeng, Panisadee Avirutnan, Chunya Puttikhunt, Watchara Kasinrerk, Nopporn Sittisombut, Prida Malasit
• Format: Journal
• Published: 2020
• Subjects: Immunology and Microbiology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078815930&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/68434
• Institution: Chiang Mai University

Dengue virus assembly involves the encapsidation of genomic RNA by the capsid protein (C) and the acquisition of an envelope comprising the premembrane (prM) and envelope (E) glycoproteins. This rapid process, lacking in detectable nucleocapsid intermediates, may impose authentic C-prM-E arrangement...