Suppression of TGF-β and IL-10 receptors on self-differentiated dendritic cells by short-hairpin RNAs enhanced activation of effector T-cells against cholangiocarcinoma cells

Suppression of TGF-β and IL-10 receptors on self-differentiated dendritic cells by short-hairpin RNAs enhanced activation of effector T-cells against cholangiocarcinoma cells

© 2020, © 2020 Mahidol University. Cholangiocarcinoma (CCA) is an aggressive tumor that is associated with high rates of recurrence and mortality. This is due, in part, to the fact that CCA cells and their microenvironment secrete immunosuppressive cytokines, transforming growth factor-β (TGF-β) and...

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Bibliographic Details
Main Authors: Chutamas Thepmalee, Aussara Panya, Jatuporn Sujjitjoon, Nunghathai Sawasdee, Naravat Poungvarin, Mutita Junking, Pa Thai Yenchitsomanus
Format: Journal
Published: 2020
Subjects:
Immunology and Microbiology
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078434181&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/68435
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078434181&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/68435

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