The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner

© 2019 International Society for Magnetic Resonance in Medicine Purpose: To demonstrate the feasibility of pseudo-continuous arterial-spin–labeled (pCASL) imaging with 3D fast-spin-echo stack-of-spirals on a compact 3T scanner (C3T), to perform trajectory correction for eddy-current–induced deviatio...

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Main Authors: Daehun Kang, Uten Yarach, Myung Ho In, Erin M. Gray, Joshua D. Trzasko, Hang Joon Jo, Yunhong Shu, John Huston, Matt A. Bernstein
Format: Journal
Published: 2020
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http://cmuir.cmu.ac.th/jspui/handle/6653943832/68468
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-684682020-04-02T15:27:56Z The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner Daehun Kang Uten Yarach Myung Ho In Erin M. Gray Joshua D. Trzasko Hang Joon Jo Yunhong Shu John Huston Matt A. Bernstein Medicine © 2019 International Society for Magnetic Resonance in Medicine Purpose: To demonstrate the feasibility of pseudo-continuous arterial-spin–labeled (pCASL) imaging with 3D fast-spin-echo stack-of-spirals on a compact 3T scanner (C3T), to perform trajectory correction for eddy-current–induced deviations in the spiral readout of pCASL imaging, and to assess the correction effect on perfusion-related images with high-performance gradients (80 mT/m, 700T/m/s) of the C3T. Methods: To track eddy-current–induced artifacts with Archimedean spiral readout, the spiral readout in pCASL imaging was performed with 5 different peak gradient slew rate (Smax) values ranging from 70 to 500 T/m/s. The trajectory for each Smax was measured using a dynamic field camera and applied in a density-compensated gridding image reconstruction in addition to the nominal trajectory. The effect of the trajectory correction was assessed with perfusion-weighted (ΔM) images and proton-density–weighted images as well as cerebral blood flow (CBF) maps, obtained from 10 healthy volunteers. Results: Blurring artifact on ΔM images was mitigated by the trajectory correction. CBF values on the left and right calcarine cortices showed no significant difference after correction. Also, the signal-to-noise ratio of ΔM images improved, on average, by 7.6% after correction (P <.001). The greatest improvement of 12.1% on ΔM images was achieved with a spiral readout using Smax of 300~400 T/m/s. Conclusion: Eddy currents can cause spiral trajectory deviation, which leads to deformation of the CBF map even in cases of low value Smax. The trajectory correction for spiral-readout–based pCASL produces more reliable results for perfusion imaging. These results suggest that pCASL is feasible on C3T with high-performance gradients. 2020-04-02T15:27:56Z 2020-04-02T15:27:56Z 2020-07-01 Journal 15222594 07403194 2-s2.0-85076378137 10.1002/mrm.28110 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85076378137&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/68468
institution Chiang Mai University
building Chiang Mai University Library
country Thailand
collection CMU Intellectual Repository
topic Medicine
spellingShingle Medicine
Daehun Kang
Uten Yarach
Myung Ho In
Erin M. Gray
Joshua D. Trzasko
Hang Joon Jo
Yunhong Shu
John Huston
Matt A. Bernstein
The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner
description © 2019 International Society for Magnetic Resonance in Medicine Purpose: To demonstrate the feasibility of pseudo-continuous arterial-spin–labeled (pCASL) imaging with 3D fast-spin-echo stack-of-spirals on a compact 3T scanner (C3T), to perform trajectory correction for eddy-current–induced deviations in the spiral readout of pCASL imaging, and to assess the correction effect on perfusion-related images with high-performance gradients (80 mT/m, 700T/m/s) of the C3T. Methods: To track eddy-current–induced artifacts with Archimedean spiral readout, the spiral readout in pCASL imaging was performed with 5 different peak gradient slew rate (Smax) values ranging from 70 to 500 T/m/s. The trajectory for each Smax was measured using a dynamic field camera and applied in a density-compensated gridding image reconstruction in addition to the nominal trajectory. The effect of the trajectory correction was assessed with perfusion-weighted (ΔM) images and proton-density–weighted images as well as cerebral blood flow (CBF) maps, obtained from 10 healthy volunteers. Results: Blurring artifact on ΔM images was mitigated by the trajectory correction. CBF values on the left and right calcarine cortices showed no significant difference after correction. Also, the signal-to-noise ratio of ΔM images improved, on average, by 7.6% after correction (P <.001). The greatest improvement of 12.1% on ΔM images was achieved with a spiral readout using Smax of 300~400 T/m/s. Conclusion: Eddy currents can cause spiral trajectory deviation, which leads to deformation of the CBF map even in cases of low value Smax. The trajectory correction for spiral-readout–based pCASL produces more reliable results for perfusion imaging. These results suggest that pCASL is feasible on C3T with high-performance gradients.
format Journal
author Daehun Kang
Uten Yarach
Myung Ho In
Erin M. Gray
Joshua D. Trzasko
Hang Joon Jo
Yunhong Shu
John Huston
Matt A. Bernstein
author_facet Daehun Kang
Uten Yarach
Myung Ho In
Erin M. Gray
Joshua D. Trzasko
Hang Joon Jo
Yunhong Shu
John Huston
Matt A. Bernstein
author_sort Daehun Kang
title The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner
title_short The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner
title_full The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner
title_fullStr The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner
title_full_unstemmed The effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3T scanner
title_sort effect of spiral trajectory correction on pseudo-continuous arterial spin labeling with high-performance gradients on a compact 3t scanner
publishDate 2020
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85076378137&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/68468
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