Correlation of the vancomycin 24-h area under the concentration-time curve (AUC<inf>24</inf>) and trough serum concentration in children with severe infection: A clinical pharmacokinetic study

• Main Authors: Satja Issaranggoon na Ayuthaya, Wasan Katip, Peninnah Oberdorfer, Aroonrut Lucksiri
• Format: Journal
• Published: 2020
• Subjects: Medicine
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85078982230&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/68476
• Institution: Chiang Mai University

© 2020 The Author(s) Background: Vancomycin is a common drug used in children with severe infection. In adults, at least 15 mg/L of the optimal vancomycin trough concentration (Ctrough) is needed to generate the target 24-h area under the concentration-time curve (AUC24) to the minimum inhibitory co...