Quantitative Prediction of CYP3A4- and CYP3A5-Mediated Drug Interactions

Quantitative Prediction of CYP3A4- and CYP3A5-Mediated Drug Interactions

© 2019 Eli Lilly and Company. Clinical Pharmacology & Therapeutics © 2019 American Society for Clinical Pharmacology and Therapeutics. We verified a physiologically-based pharmacokinetic (PBPK) model to predict cytochrome P450 3A4/5-mediated drug-drug interactions (DDIs). A midazolam (MDZ)–ket...

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Bibliographic Details
Main Authors: Yingying Guo, Aroonrut Lucksiri, Gemma L. Dickinson, Raj K. Vuppalanchi, Janna K. Hilligoss, Stephen D. Hall
Format: Journal
Published: 2020
Subjects:
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85073807563&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/68538
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85073807563&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/68538

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