Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice.
“Veterinary Integrative Sciences” is the official peer-reviewed journal of the Faculty of Veterinary Medicine, Chiang Mai University, Thailand. The primary aim of the journal is to facilitate and oversee the publication of a wide-range of high quality academic articles with an overall integration of...
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Faculty of Veterinary Medicine,ChiangMai Universitity
2020
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| Online Access: | https://he02.tci-thaijo.org/index.php/vis/article/view/240589/164287 http://cmuir.cmu.ac.th/jspui/handle/6653943832/68630 |
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th-cmuir.6653943832-686302020-05-20T04:41:49Z Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. Tanagorn Pintapagung Thanaporn Asawapattanakul Antioxidant Chia seed Salvia hispanica L. Wound healing “Veterinary Integrative Sciences” is the official peer-reviewed journal of the Faculty of Veterinary Medicine, Chiang Mai University, Thailand. The primary aim of the journal is to facilitate and oversee the publication of a wide-range of high quality academic articles with an overall integration of the various areas of animal and veterinary sciences Salvia hispanica L. either commonly known as chia seed, can help in inflammatory skin disease including wound healing. However, the pharmacological activity and benefits of chia seed for wound healing need to be validated. The current study is designed to evaluate the effect of different concentrations of chia seed extract used as a topical drug for secondary wound healing in mice. Chia seed extract was analysed some active ingredients and properties, such as fatty acid compositions, total phenolic content, antioxidant activity, and antimicrobial activity. Male BALB/cAJcl mice were divided into 4 groups (n = 24), given 6 mm circular area, treated for 9 consecutive days with different applications: propylene glycol, 4% chia seed extract, 8% chia seed extract, and 1% silver sulfadiazine. The investigated parameters were the percentage of wound contraction and histopathological examination. Chia seed extract consists of major fatty acids, alpha-linolenic and linoleic acid; total phenolic compound, also has ability to eliminate free radicals by using DPPH, FRAP, and ABTS assay, and did not show the antibacterial property. Wound contraction increased significantly on day 9 in groups treated with 8%, 4% v/v chia seed extract, and 1% silver-sulfadiazine, rising to 97.98, 97.14, 89.17 percent respectively, compared to propylene glycol group, 76.49 (P<0.001). Histopathological studies showed infiltration of a number of fibroblasts, collagen, and ves-sels occurring in the treated groups. Chia seed extract is a good natural plant which could be used as topical treatment for activating wound healing. 2020-05-20T04:41:49Z 2020-05-20T04:41:49Z 2020 Veterinary Integrative Sciences (Vet Integr Sci) 18, 2 (May-Aug 2019), p.1-15 2629-9968 https://he02.tci-thaijo.org/index.php/vis/article/view/240589/164287 http://cmuir.cmu.ac.th/jspui/handle/6653943832/68630 Eng Faculty of Veterinary Medicine,ChiangMai Universitity |
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Thailand Thailand |
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English |
| topic |
Antioxidant Chia seed Salvia hispanica L. Wound healing |
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Antioxidant Chia seed Salvia hispanica L. Wound healing Tanagorn Pintapagung Thanaporn Asawapattanakul Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. |
| description |
“Veterinary Integrative Sciences” is the official peer-reviewed journal of the Faculty of Veterinary Medicine, Chiang Mai University, Thailand. The primary aim of the journal is to facilitate and oversee the publication of a wide-range of high quality academic articles with an overall integration of the various areas of animal and veterinary sciences |
| author |
Tanagorn Pintapagung Thanaporn Asawapattanakul |
| author_facet |
Tanagorn Pintapagung Thanaporn Asawapattanakul |
| author_sort |
Tanagorn Pintapagung |
| title |
Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. |
| title_short |
Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. |
| title_full |
Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. |
| title_fullStr |
Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. |
| title_full_unstemmed |
Effect of chia (Salvia hispanica L.) seed extract on wound healing in mice. |
| title_sort |
effect of chia (salvia hispanica l.) seed extract on wound healing in mice. |
| publisher |
Faculty of Veterinary Medicine,ChiangMai Universitity |
| publishDate |
2020 |
| url |
https://he02.tci-thaijo.org/index.php/vis/article/view/240589/164287 http://cmuir.cmu.ac.th/jspui/handle/6653943832/68630 |
| _version_ |
1681752660178370560 |