Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions
Chiang Mai University (CMU) Journal of Natural Sciences is dedicated to the publication of original research in Sciences & Technology and the Health Sciences. Submissions are welcomed from CMU, as well as other Thai and foreign institutions. All submissions must be original research not previous...
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th-cmuir.6653943832-686752020-05-20T04:41:51Z Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions Farzaneh Mohamadpour Formic acid Natural green and Bio-based catalyst 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Solvent-free conditions Chiang Mai University (CMU) Journal of Natural Sciences is dedicated to the publication of original research in Sciences & Technology and the Health Sciences. Submissions are welcomed from CMU, as well as other Thai and foreign institutions. All submissions must be original research not previously published or simultaneously submitted for publication. Manuscripts are peer reviewed using the double -blinded review system by at least 2 reviewers before acceptance. The CMU Journal of Natural Sciences is published four times a year, in January, April, July and October. A green synthetic route to the facile Biginelli synthesis of 2-oxo- and thioxo-1,2,3,4-tetrahydropyrimidines have been developed using formic acid as a natural green and bio-based catalyst under solvent-free reaction conditions. All reactions are completed in a short period of times and the products are obtained in high to excellent yields. The salient features of this green approach are simple work-up with no necessity of chromatographic purification steps, absence of hazardous organic solvents, use of safe, non-volatile, noncorrosive and readily green catalyst, solvent-free conditions, one-pot reaction, ecofriendly and clean synthesis. 2020-05-20T04:41:51Z 2020-05-20T04:41:51Z 2020 Chiang Mai University (CMU) Journal of Natural Sciences 19,1 (Jan-Mar 2020), p.61-75 2465-4337 http://cmuj.cmu.ac.th/uploads/journal_list_index/993551253.pdf http://cmuir.cmu.ac.th/jspui/handle/6653943832/68675 Eng Chiang Mai University |
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Formic acid Natural green and Bio-based catalyst 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Solvent-free conditions |
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Formic acid Natural green and Bio-based catalyst 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Solvent-free conditions Farzaneh Mohamadpour Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions |
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Chiang Mai University (CMU) Journal of Natural Sciences is dedicated to the publication of original research in Sciences & Technology and the Health Sciences. Submissions are welcomed from CMU, as well as other Thai and foreign institutions. All submissions must be original research not previously published or simultaneously submitted for publication. Manuscripts are peer reviewed using the double -blinded review system by at least 2 reviewers before acceptance. The CMU Journal of Natural Sciences is published four times a year, in January, April, July and October. |
author |
Farzaneh Mohamadpour |
author_facet |
Farzaneh Mohamadpour |
author_sort |
Farzaneh Mohamadpour |
title |
Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions |
title_short |
Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions |
title_full |
Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions |
title_fullStr |
Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions |
title_full_unstemmed |
Environmentally Friendly and Facile Synthesis of 2-oxo- and Thioxo-1,2,3,4-tetrahydropyrimidines Catalyzed by Formic Acid as a Natural Green and Bio-based Catalyst under Solvent-Free Conditions |
title_sort |
environmentally friendly and facile synthesis of 2-oxo- and thioxo-1,2,3,4-tetrahydropyrimidines catalyzed by formic acid as a natural green and bio-based catalyst under solvent-free conditions |
publisher |
Chiang Mai University |
publishDate |
2020 |
url |
http://cmuj.cmu.ac.th/uploads/journal_list_index/993551253.pdf http://cmuir.cmu.ac.th/jspui/handle/6653943832/68675 |
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1681752675019915264 |