Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology
Chiang Mai Journal of Science
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Faculty of Science, Chiang Mai University
2020
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| Online Access: | https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=10921 http://cmuir.cmu.ac.th/jspui/handle/6653943832/68750 |
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th-cmuir.6653943832-687502020-06-10T07:12:28Z Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology Qin Ou-Yang Hui-Ling Yang Wei Zhu Phyllanthusurinaria L. corilagin geraniin response surface methodology Chiang Mai Journal of Science Phyllanthus urinaria L. (P. urinaria) is one kind of traditional Chinese medicine with many bioactivities. Corilagin and geraniin are the major compounds with bioactivities in P. urinaria. Response surface methodology(RSM) was used to optimize the best conditions during the extraction process of corilagin and geraniin. By single-factor experiments, four variables of extraction were investigated. Then a Box–Behnken central composite design consisting of 29 experimental runs and 5 replicates, at the zero point was applied, and a regression model was used to predict the optimal extraction yield. The optimal conditions were as follows: ethanol concentration 65.38%, liquid/solid ratio 20.14:1, extraction temperature 81.55°C, and time 2.46 h. Under the optimal conditions, the experimental value was consistent with the predicted response value, which indicates that response surface methodology is a feasible method that was validated for optimization of the extraction of corilagin and geraniol from P. urinaria. 2020-06-10T07:12:28Z 2020-06-10T07:12:28Z 2020 Chiang Mai Journal of Science 47,3 (May 2020), p.513-529 2465-3845 https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=10921 http://cmuir.cmu.ac.th/jspui/handle/6653943832/68750 Eng Faculty of Science, Chiang Mai University |
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Chiang Mai University Library |
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Asia |
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Thailand Thailand |
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English |
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Phyllanthusurinaria L. corilagin geraniin response surface methodology |
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Phyllanthusurinaria L. corilagin geraniin response surface methodology Qin Ou-Yang Hui-Ling Yang Wei Zhu Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology |
| description |
Chiang Mai Journal of Science |
| author |
Qin Ou-Yang Hui-Ling Yang Wei Zhu |
| author_facet |
Qin Ou-Yang Hui-Ling Yang Wei Zhu |
| author_sort |
Qin Ou-Yang |
| title |
Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology |
| title_short |
Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology |
| title_full |
Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology |
| title_fullStr |
Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology |
| title_full_unstemmed |
Optimization of Corilagin and Geraniin Extraction from Phyllanthus urinaria L. by Response Surface Methodology |
| title_sort |
optimization of corilagin and geraniin extraction from phyllanthus urinaria l. by response surface methodology |
| publisher |
Faculty of Science, Chiang Mai University |
| publishDate |
2020 |
| url |
https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=10921 http://cmuir.cmu.ac.th/jspui/handle/6653943832/68750 |
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