Synthesis, antituberculosis activity and molecular docking studies for novel naphthoquinone derivatives

• المؤلفون الرئيسيون: Paengsri W., Lee V.S., Chong W.L., Wahab H.A., Baramee A.
• التنسيق: مقال
• اللغة: English
• منشور في: 2014
• الوصول للمادة أونلاين: http://www.scopus.com/inward/record.url?eid=2-s2.0-84869770338&partnerID=40&md5=0d1657de16e2c92cf1f2b31ec8c3d42a; http://cmuir.cmu.ac.th/handle/6653943832/6938
• المؤسسة: Chiang Mai University

A series of new substituted derivatives of 2-hydroxy-l, 4-naphthoquinone were successfully prepared by a Mannich reaction and evaluated for their in vitro anti-tuberculosis activity against Mycobacterium tuberculosis H37Ra. All the compounds were tested by Green Fluorescent Protein Microplate Assay...