Synthesis, antituberculosis activity and molecular docking studies for novel naphthoquinone derivatives

A series of new substituted derivatives of 2-hydroxy-l, 4-naphthoquinone were successfully prepared by a Mannich reaction and evaluated for their in vitro anti-tuberculosis activity against Mycobacterium tuberculosis H37Ra. All the compounds were tested by Green Fluorescent Protein Microplate Assay...

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Bibliographic Details
Main Authors: W. Paengsri, V. S. Lee, W. L. Chong, H. A. Wahab, A. Baramee
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84869770338&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51334
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Institution: Chiang Mai University