Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process

The Chiang Mai Journal of Science is an international English language peer-reviewed journal which is published in open access electronic format 6 times a year in January, March, May, July, September and November by the Faculty of Science, Chiang Mai University. Manuscripts in most areas of science...

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Main Authors: Autcharaporn Srion, Phee Palanuruksa, Faungchat Thammarakcharoen, Jintamai Suwanprateeb
Language:English
Published: Faculty of Science, Chiang Mai University 2020
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Online Access:https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=11112
http://cmuir.cmu.ac.th/jspui/handle/6653943832/69880
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-698802020-10-08T08:36:16Z Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process Autcharaporn Srion Phee Palanuruksa Faungchat Thammarakcharoen Jintamai Suwanprateeb brushite hydroxyapatite bone graft resorption three dimensional printing The Chiang Mai Journal of Science is an international English language peer-reviewed journal which is published in open access electronic format 6 times a year in January, March, May, July, September and November by the Faculty of Science, Chiang Mai University. Manuscripts in most areas of science are welcomed except in areas such as agriculture, engineering and medical science which are outside the scope of the Journal. Currently, we focus on manuscripts in biology, chemistry, physics, materials science and environmental science. Papers in mathematics statistics and computer science are also included but should be of an applied nature rather than purely theoretical. Manuscripts describing experiments on humans or animals are required to provide proof that all experiments have been carried out according to the ethical regulations of the respective institutional and/or governmental authorities and this should be clearly stated in the manuscript itself. The Editor reserves the right to reject manuscripts that fail to do so. Hydroxyapatite (HA) is widely used as bone graft, but showed limited resorption in the body which could affect its bone integration. In addition to HA, dicalcium phosphate dihydrate or brushite had greater resorption rate and was reported to be biocompatible and osteoconductive. Fabrication of brushite was experimentally carried out by using a combination of a powder-based three dimensional printing (3DP) technique and a phase transformation by a dissolution-precipitation process. The 3D printed calcium sulfate based sample was soaked in 1M disodium hydrogen phosphate solution at various conditions by varying pH (6 and 7), temperature (25˚C, 37˚C and 80˚C) and time (24, 48 and 72 hours). X-ray diffraction showed that brushite could be obtained by using pH 7 and 37 ˚C at all soaking durations and the crystal shape was observed to be plate-like. Samples were damaged at 80˚C for both pH values. For other conditions, brushite was found as a major phase in the converted samples, but the samples still contained calcium sulfate dihydrate and monetite as minor phases. However, the amount of brushite phase increased with increasing conversion times. Resorbability of the 3D printed brushite was evaluated by measuring a weight loss and calcium and phosphorus ion releasing in simulated body fluid at pH 7.4 and 37˚C for up to 28 days. Weight loss of the sample was high initially for up to 7 days and leveled off afterward. The total weight loss was approximately 43% at 28 days. 3D printed brushite was also found to transform to other calcium phosphate phases during resorption process. Hydroxyapatite was detected at the surface region while a mixture of hydroxyapatite and octacalcium phosphate was found in the core area. This phase transformation could be associated with the release of calcium and phosphate ions from specimens during resorption and re-precipitation into different phases under desired conditions for each phase. 2020-10-08T08:36:16Z 2020-10-08T08:36:16Z 2020 Chiang Mai Journal of Science 47,4 (Special Issue II : July 2020), p.738-751 2465-3845 https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=11112 http://cmuir.cmu.ac.th/jspui/handle/6653943832/69880 Eng Faculty of Science, Chiang Mai University
institution Chiang Mai University
building Chiang Mai University Library
continent Asia
country Thailand
Thailand
content_provider Chiang Mai University Library
collection CMU Intellectual Repository
language English
topic brushite
hydroxyapatite
bone graft
resorption
three dimensional printing
spellingShingle brushite
hydroxyapatite
bone graft
resorption
three dimensional printing
Autcharaporn Srion
Phee Palanuruksa
Faungchat Thammarakcharoen
Jintamai Suwanprateeb
Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process
description The Chiang Mai Journal of Science is an international English language peer-reviewed journal which is published in open access electronic format 6 times a year in January, March, May, July, September and November by the Faculty of Science, Chiang Mai University. Manuscripts in most areas of science are welcomed except in areas such as agriculture, engineering and medical science which are outside the scope of the Journal. Currently, we focus on manuscripts in biology, chemistry, physics, materials science and environmental science. Papers in mathematics statistics and computer science are also included but should be of an applied nature rather than purely theoretical. Manuscripts describing experiments on humans or animals are required to provide proof that all experiments have been carried out according to the ethical regulations of the respective institutional and/or governmental authorities and this should be clearly stated in the manuscript itself. The Editor reserves the right to reject manuscripts that fail to do so.
author Autcharaporn Srion
Phee Palanuruksa
Faungchat Thammarakcharoen
Jintamai Suwanprateeb
author_facet Autcharaporn Srion
Phee Palanuruksa
Faungchat Thammarakcharoen
Jintamai Suwanprateeb
author_sort Autcharaporn Srion
title Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process
title_short Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process
title_full Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process
title_fullStr Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process
title_full_unstemmed Low Temperature Fabrication of Brushite by PowderBased Three Dimensional Printing Coupled with Phase Transformation Process
title_sort low temperature fabrication of brushite by powderbased three dimensional printing coupled with phase transformation process
publisher Faculty of Science, Chiang Mai University
publishDate 2020
url https://epg.science.cmu.ac.th/ejournal/dl.php?journal_id=11112
http://cmuir.cmu.ac.th/jspui/handle/6653943832/69880
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