Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. One new limonoid, named siamensinolide (1), together with two known limonoids (2 and 3) and eight carbazole alkaloids (4–11) were isolated from the twigs of Chalcas siamensis Tanaka. Their structures were elucidated by spect...

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Main Authors:	Sirada Boonyaketgoson, Vatcharin Rukachaisirikul, Souwalak Phongpaichit, Kongkiat Trisuwan
Format:	Journal
Published:	2020
Subjects:	Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology Chemistry
Online Access:	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086018043&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70088
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Institution:	Chiang Mai University

id	th-cmuir.6653943832-70088
record_format	dspace
spelling	th-cmuir.6653943832-700882020-10-14T08:29:41Z Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka Sirada Boonyaketgoson Vatcharin Rukachaisirikul Souwalak Phongpaichit Kongkiat Trisuwan Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology Chemistry © 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. One new limonoid, named siamensinolide (1), together with two known limonoids (2 and 3) and eight carbazole alkaloids (4–11) were isolated from the twigs of Chalcas siamensis Tanaka. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopy. O-methylclausenolide (2) displayed strong cytotoxicity against A2780 cell lines with the IC50 value of 9.2 µM, while clausenolide (3) exhibited strong antibacterial activity against methicillin-resistant Staphylococcus aureus with the MIC value of 0.5 µg/mL. 2020-10-14T08:24:12Z 2020-10-14T08:24:12Z 2020-01-01 Journal 14786427 14786419 2-s2.0-85086018043 10.1080/14786419.2020.1768084 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086018043&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70088
institution	Chiang Mai University
building	Chiang Mai University Library
continent	Asia
country	Thailand Thailand
content_provider	Chiang Mai University Library
collection	CMU Intellectual Repository
topic	Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology Chemistry
spellingShingle	Agricultural and Biological Sciences Biochemistry, Genetics and Molecular Biology Chemistry Sirada Boonyaketgoson Vatcharin Rukachaisirikul Souwalak Phongpaichit Kongkiat Trisuwan Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
description	© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. One new limonoid, named siamensinolide (1), together with two known limonoids (2 and 3) and eight carbazole alkaloids (4–11) were isolated from the twigs of Chalcas siamensis Tanaka. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopy. O-methylclausenolide (2) displayed strong cytotoxicity against A2780 cell lines with the IC50 value of 9.2 µM, while clausenolide (3) exhibited strong antibacterial activity against methicillin-resistant Staphylococcus aureus with the MIC value of 0.5 µg/mL.
format	Journal
author	Sirada Boonyaketgoson Vatcharin Rukachaisirikul Souwalak Phongpaichit Kongkiat Trisuwan
author_facet	Sirada Boonyaketgoson Vatcharin Rukachaisirikul Souwalak Phongpaichit Kongkiat Trisuwan
author_sort	Sirada Boonyaketgoson
title	Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
title_short	Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
title_full	Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
title_fullStr	Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
title_full_unstemmed	Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka
title_sort	limonoids and carbazole alkaloids from the twigs of chalcas siamensis tanaka
publishDate	2020
url	https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85086018043&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70088
_version_	1681752839035027456

Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka

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