Metformin preferentially provides neuroprotection following cardiac ischemia/reperfusion in non-diabetic rats

• Main Authors: Juthipong Benjanuwattra, Nattayaporn Apaijai, Titikorn Chunchai, Sasiwan Kerdphoo, Thidarat Jaiwongkam, Bussarin Arunsak, Supawit Wongsuchai, Nipon Chattipakorn, Siriporn C. Chattipakorn
• Format: Journal
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85089364798&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70162
• Institution: Chiang Mai University

Copyright © 2020 Elsevier B.V. All rights reserved. Following acute myocardial infarction, re-establishment of coronary perfusion aggravates further injuries in the heart and remote organs including the brain as a consequence of ischemia/reperfusion (I/R) injury. Since pretreatment with metformin at...