Impact of albumin and omeprazole on steady-state population pharmacokinetics of voriconazole and development of a voriconazole dosing optimization model in thai patients with hematologic diseases

• المؤلفون الرئيسيون: Buddharat Khan-Asa, Baralee Punyawudho, Noppaket Singkham, Piyawat Chaivichacharn, Ekapun Karoopongse, Methee Chayakulkeeree, Preecha Montakantikul
• التنسيق: دورية
• منشور في: 2020
• الموضوعات: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• الوصول للمادة أونلاين: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85090543166&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70185

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This study aimed to identify factors that significantly influence the pharmacokinetics of voriconazole in Thai adults with hematologic diseases, and to determine optimal voriconazole dosing regimens. Blood samples were collected at steady sta...