Occupation of a thermoresistant-scaffold (αRep) at SP1-NC cleavage site disturbs the function of HIV-1 protease

• Main Authors: Sudarat Hadpech, Nichakan Peerakam, Koollawat Chupradit, Chatchai Tayapiwatana
• Format: Journal
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85087096640&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/70227
• Institution: Chiang Mai University

© 2020 Portland Press Ltd. All rights reserved. HIV-1 nucleocapsid (NC) becomes an attractive target for the development of novel anti-HIV-1 agents. Discovering of non-antibody scaffolds that disrupt the function of NC will be a potential aspect for disturbing viral maturation process. Corresponding...