A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform

© 2020, Chiang Mai University. All rights reserved. Giving good stability and sensitivity of the low-cost electrochemical immunosensor is achieved using a conducting poly(pyrrole-3-carboxylic acid) (PP3C) film on a screen-printed carbon electrode (SPCE). The PP3C film offers high density surface car...

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Main Authors: Supakiet Chanarsa, Chammari Pothipor, Nawee Kungwan, Kontad Ounnunkad
Format: Journal
Published: 2020
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083707601&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70263
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Institution: Chiang Mai University
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spelling th-cmuir.6653943832-702632020-10-14T08:40:14Z A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform Supakiet Chanarsa Chammari Pothipor Nawee Kungwan Kontad Ounnunkad Biochemistry, Genetics and Molecular Biology Chemistry Materials Science Mathematics © 2020, Chiang Mai University. All rights reserved. Giving good stability and sensitivity of the low-cost electrochemical immunosensor is achieved using a conducting poly(pyrrole-3-carboxylic acid) (PP3C) film on a screen-printed carbon electrode (SPCE). The PP3C film offers high density surface carboxylic groups, on which can be covalently conjugated with capturing antibodies, and improves electrode reactivity. Our simple immunosensor exhibitessatisfactory sensitivity, selectivity, stability, reproducibility, and regenerability for the detection of human immunoglobulin G (IgG). The proposed sensitive immunosensor provides a detection limit of 0.120 ng mL-1 and a sensitivity of 3.61 µA cm-2 mL ng-1, which thus is promising for clinical applications. 2020-10-14T08:26:37Z 2020-10-14T08:26:37Z 2020-01-01 Journal 01252526 2-s2.0-85083707601 https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083707601&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/70263
institution Chiang Mai University
building Chiang Mai University Library
continent Asia
country Thailand
Thailand
content_provider Chiang Mai University Library
collection CMU Intellectual Repository
topic Biochemistry, Genetics and Molecular Biology
Chemistry
Materials Science
Mathematics
spellingShingle Biochemistry, Genetics and Molecular Biology
Chemistry
Materials Science
Mathematics
Supakiet Chanarsa
Chammari Pothipor
Nawee Kungwan
Kontad Ounnunkad
A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
description © 2020, Chiang Mai University. All rights reserved. Giving good stability and sensitivity of the low-cost electrochemical immunosensor is achieved using a conducting poly(pyrrole-3-carboxylic acid) (PP3C) film on a screen-printed carbon electrode (SPCE). The PP3C film offers high density surface carboxylic groups, on which can be covalently conjugated with capturing antibodies, and improves electrode reactivity. Our simple immunosensor exhibitessatisfactory sensitivity, selectivity, stability, reproducibility, and regenerability for the detection of human immunoglobulin G (IgG). The proposed sensitive immunosensor provides a detection limit of 0.120 ng mL-1 and a sensitivity of 3.61 µA cm-2 mL ng-1, which thus is promising for clinical applications.
format Journal
author Supakiet Chanarsa
Chammari Pothipor
Nawee Kungwan
Kontad Ounnunkad
author_facet Supakiet Chanarsa
Chammari Pothipor
Nawee Kungwan
Kontad Ounnunkad
author_sort Supakiet Chanarsa
title A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
title_short A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
title_full A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
title_fullStr A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
title_full_unstemmed A poly(Pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
title_sort poly(pyrrole-3-carboxylic acid) thin film modified screen printed carbon electrode as highly sensitive and selective label-free electrochemical immunosensing platform
publishDate 2020
url https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85083707601&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/70263
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