Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla

Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited an...

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Main Authors:	Cheenpracha S., Ritthiwigrom T., Laphookhieo S.
Format:	Article
Language:	English
Published:	2014
Online Access:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84876930059&partnerID=40&md5=6bb55324c28f2cae48738bbf7b4415ad http://cmuir.cmu.ac.th/handle/6653943832/7047
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Institution:	Chiang Mai University
Language:	English

id	th-cmuir.6653943832-7047
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spelling	th-cmuir.6653943832-70472014-08-30T03:51:31Z Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla Cheenpracha S. Ritthiwigrom T. Laphookhieo S. Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy. 2014-08-30T03:51:31Z 2014-08-30T03:51:31Z 2013 Article 01633864 10.1021/np3006937 23806072 JNPRD http://www.scopus.com/inward/record.url?eid=2-s2.0-84876930059&partnerID=40&md5=6bb55324c28f2cae48738bbf7b4415ad http://cmuir.cmu.ac.th/handle/6653943832/7047 English
institution	Chiang Mai University
building	Chiang Mai University Library
country	Thailand
collection	CMU Intellectual Repository
language	English
description	Chemical investigation of an alkaloidal extract of Alstonia macrophylla bark led to the isolation and identification of two new nitrogenous derivatives, alstoniaphyllines A (1) and B (2), a new indole alkaloid, alstoniaphylline C (4), and eight known alkaloids (3, 5-11). Alstonisine (9) exhibited antiplasmodial activity against Plasmodium falciparum, with an IC50 of 7.6 μM. © 2013 The American Chemical Society and American Society of Pharmacognosy.
format	Article
author	Cheenpracha S. Ritthiwigrom T. Laphookhieo S.
spellingShingle	Cheenpracha S. Ritthiwigrom T. Laphookhieo S. Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
author_facet	Cheenpracha S. Ritthiwigrom T. Laphookhieo S.
author_sort	Cheenpracha S.
title	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_short	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_full	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_fullStr	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_full_unstemmed	Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla
title_sort	alstoniaphyllines a-c, unusual nitrogenous derivatives from the bark of alstonia macrophylla
publishDate	2014
url	http://www.scopus.com/inward/record.url?eid=2-s2.0-84876930059&partnerID=40&md5=6bb55324c28f2cae48738bbf7b4415ad http://cmuir.cmu.ac.th/handle/6653943832/7047
_version_	1681420727786405888

Alstoniaphyllines A-C, unusual nitrogenous derivatives from the bark of Alstonia macrophylla

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